“Anacondas: Trail of Blood” is a 2009 horror movie directed by Don E. FauntLeRoy. It is the fourth installment in the “Anaconda” film series and a direct sequel to “Anaconda 3: Offspring.”

The movie follows a group of genetically modified anacondas that have been released into the wild and are now causing havoc in a small town. A team of scientists, led by Dr. Amanda Haze (Crystal Allen), is brought in to hunt down the snakes and find out who is behind their creation.

As the team sets out to track down the anacondas, they soon realize that they are not the only ones on their trail. A group of mercenaries, led by Hammett (John Rhys-Davies), is also after the snakes, but for a very different reason.

As the two groups race to find the anacondas, they soon find themselves in a deadly battle with the giant serpents. With the help of a local police officer, Lieutenant Stack (Linden Ashby), the scientists must find a way to stop the anacondas before they can escape into the wider world and cause even more destruction.